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Humans become infected by coming in contact
with animals or animal products that are contaminated with this bacterium. In humans brucellosis can cause a range of
symptoms that are similar to the flu and may include fever, sweats, headaches, back pains, and physical weakness. Severe
infections of the central nervous systems or lining of the heart may occur. Brucellosis can also cause long-lasting
or chronic symptoms that include recurrent fevers, joint pain, and fatigue. The global burden
of human brucellosis remains enormous; it causes more than 500,000 infections per year worldwide. The annual number of reported
cases in United States (now approximately 100 cases) has dropped significantly because of aggressive animal vaccination programs
and milk pasteurization. Most of the US cases are now due to the consumption of illegally imported unpasteurized dairy products
from Mexico. Approximately 60% of human brucellosis cases in the United States now occur in California and Texas.
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